您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Lifitegrast(SAR 1118 SHP-606)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Lifitegrast(SAR 1118 SHP-606)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Lifitegrast(SAR 1118 SHP-606)图片
CAS NO:1025967-78-5
规格:≥98%
包装与价格:
包装价格(元)
25mg电议
50mg电议
100mg电议
250mg电议
500mg电议

产品介绍

Description: Lifitegrast (formerly SAR 1118; SAR 1118-023; SAR-1118; trade nameXiidra) is a novel and potent integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist approved in 2016 for the the treatment of Dry Eye Disease. It inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM. It inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.

References: Lifitegrast, a Novel Integrin Antagonist for Treatment of Dry Eye Disease. Ocul Surf. 2016 Apr;14(2):207-15. [2]. Sun Y, et al. Corneal inflammation is inhibited by the LFA-1 antagonist, lifitegrast (SAR 1118). J Ocul Pharmacol Ther. 2013 May;29(4):395-402

Related CAS #: 1025967-78-5 (free) 1119276-80-0 (sodium salt)

纯度:≥98%

CAS:1025967-78-5