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(R)-PS210
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:1410101-89-1
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-specific allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment. References: [1]. Wilhelm A, et al. 2-(3-Oxo-1,3-diphenylpropyl)malonic acids as potent allosteric ligands of the PIF pocket of phosphoinositide-dependent kinase-1: development and prodrug concept.J Med Chem. 2012 Nov 26;55(22):9817-30.

纯度:≥98%

CAS:1410101-89-1