CAS NO: | 1410101-89-1 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
(R)-PS210, the R enantiomer of PS210 (compound 4h-eutomer), is a substrate-specific allosteric activator of PDK1 with an AC50 value of 1.8 μM. (R)-PS210 targets to the PIF-binding pocket of PDK1. PIF: The protein kinase C-related kinase 2 (PRK2)-interacting fragment. References: [1]. Wilhelm A, et al. 2-(3-Oxo-1,3-diphenylpropyl)malonic acids as potent allosteric ligands of the PIF pocket of phosphoinositide-dependent kinase-1: development and prodrug concept.J Med Chem. 2012 Nov 26;55(22):9817-30.
纯度:≥98%
CAS:1410101-89-1