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SB-265610
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
SB-265610图片
CAS NO:211096-49-0
规格:≥98%
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议

产品介绍

SB-265610 is a novel, potent, selective, nonpeptide, competitive, and allosteric CXCR2 antagonist that inhibits CINC-1-mediated but not C5a-mediated Ca2+ mobilization (IC50 are 3.4 and 6800 nM respectively). It inhibits CINC-induced chemotaxis and attenuates neutrophil accumulation in inflammatory lung injury in vivo. SB-265610 blocks rat cytokine-induced neutrophil chemoattractant-1 (CINC-1)-induced calcium mobilization and neutrophil chemotaxis with IC50s of 3.7 nM and 70 nM, respectively.

纯度:≥98%

CAS:211096-49-0