CAS NO: | 220847-86-9 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
Valategrast (R-411 free base) is a highly potent and orally bioavailable integrin α4β1 (VLA-4) and α4β7 dual antagonist. Valategrast has the highly potential for Chronic obstructive pulmonary disease (COPD) and asthma treatment. References: [1]. Woodside DG, et al. Cell adhesion antagonists: therapeutic potential in asthma and chronic obstructive pulmonary disease. BioDrugs. 2008;22(2):85-100.
[2]. Halland N, et al. Small Macrocycles As Highly Active Integrin α2β1 Antagonists. ACS Med Chem Lett. 2014 Jan 10;5(2):193-8.
纯度:≥98%
CAS:220847-86-9