BMS-962212 (cas:1430114-34-3) is a direct, reversible, selective factor XIa (FXIa) inhibitor and it is well tolerated, with fast onset of pharmacodynamic (PD) responses and rapid elimination. BMS-962212 increases exposure dependently in activated partial thromboplastin time. And it decreases exposure dependently in FXI clotting activity.
| 中文别名 | BMS-962212(cas:1430114-34-3) |
| 英文别名 | BMS-962212,1430114-34-3 |
| CAS号 | 1430114-34-3 |
| SMILES | ClC1=C(F)C(/C=C/C(N2[C@H](C(NC3=CC=C(C(O)=O)C=C3)=O)C(C=CC=C4N5C(CN(C)CC5)=O)=C4CC2)=O)=C(N6C=NN=N6)C=C1 |
| Inchi | InChI=1S/C32H28ClFN8O5/c1-39-15-16-40(28(44)17-39)25-4-2-3-22-21(25)13-14-41(30(22)31(45)36-20-7-5-19(6-8-20)32(46)47)27(43)12-9-23-26(42-18-35-37-38-42)11-10-24(33)29(23)34/h2-12,18,30H,13-17H2,1H3,(H,36,45)(H,46,47)/b12-9+/t30-/m0/s1 |
| InchiKey | WYFCZWSWFGJODV-MIANJLSGSA-N |
| 分子式 Formula | C32H28ClFN8O5 |
| 分子量 Molecular Weight | 659.07 |
| Polarizability极化度 | 67.9±0.5 10-24cm3 |
| 密度 Density | 1.5±0.1 g/cm3 |
| 性状 | White to off white powder |
| 储藏条件 Storage conditions | 请根据产品建议的存储条件进行存储，Please store the product under the recommended condition sin the description. |
m.cnreagent.com