PF-05231023(1037589-69-7) is a long-acting FGF21 mimetic. PF-05231023 decreases body weight and improves lipid profile in non-human primates and in type 2 diabetic subjects.
| 中文别名 | PF-05231023(cas:1037589-69-7) |
| 英文别名 | PF-05231023,1037589-69-7,PF 05231023,PF 05231023;2,5-Dihydro-2,5-dioxo-N-[2-[2-[3-oxo-3-[[4-[3-oxo-3-(2-oxo-1-azetidinyl)propyl]phenyl]amino]propoxy]ethoxy]ethyl]-1H-pyrrole-1-propanamide |
| CAS号 | 1037589-69-7 |
| SMILES | O=C(CCN1C(C=CC1=O)=O)NCCOCCOCCC(NC2=CC=C(C=C2)CCC(N3C(CC3)=O)=O)=O |
| Inchi | InChI=1S/C26H32N4O8/c31-21(9-13-29-24(34)7-8-25(29)35)27-12-16-38-18-17-37-15-11-22(32)28-20-4-1-19(2-5-20)3-6-23(33)30-14-10-26(30)36/h1-2,4-5,7-8H,3,6,9-18H2,(H,27,31)(H,28,32) |
| InchiKey | BJDLYWUPKGDHCF-UHFFFAOYSA-N |
| 分子式 Formula | C26H32N4O8 |
| 分子量 Molecular Weight | 528.55 |
| 溶解度Solubility | 生物体外In Vitro:DMSO溶解度125 mg/mL(236.50 mM;Need ultrasonic) |
| 性状 | 固体粉末,Power |
| 储藏条件 Storage conditions | -20℃ 3 years年 4℃ 2 years年 / In solvent溶液中: -80℃ 6 months月 -20℃ 1 month月 |
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