(S)-(+)-美芬妥英((S)-Mephenytoin,70989-04-7)is a substrate of the cytochrome P450 (CYP) isoform CYP2C19, also known as mephenytoin 4-hydroxylase.1 CYP2C19 metabolizes a variety of therapeutic agents, including omeprazole, proguanil, diazepam, propranolol, citalopram, imipramine, and certain barbiturates.
中文别名 | (S)-(+)-美芬妥英;Mephenytoin;70989-04-7 |
英文别名 | (S)-(+)-Mephenytoin;Mephenytoin;(S)-Mephenytoin; 70989-04-7; S-Mephenytoin; (S)-(+)-Mephenytoin;S-Mephenytoin |
CAS号 | 70989-04-7 |
SMILES | CCC1(C(=O)N(C(=O)N1)C)C2=CC=CC=C2 |
Inchi | InChI=1S/C12H14N2O2/c1-3-12(9-7-5-4-6-8-9)10(15)14(2)11(16)13-12/h4-8H,3H2,1-2H3,(H,13,16)/t12-/m0/s1 |
InchiKey | GMHKMTDVRCWUDX-LBPRGKRZSA-N |
分子式 Formula | C12H14N2O2 |
分子量 Molecular Weight | 218.3 |
性状 | crystalline solid |
储藏条件 Storage conditions | 储存条件:-20° C,避光防潮密闭干燥。 运输条件:2~8℃运输 |