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TP3011
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAS NO:534605-74-8
包装:50mg, 100mg, 250mg
规格:≥98%

产品介绍

TP3011 (CH0793011) is a major active metabolite of CH-0793076 and is a highly potent topoisomerase I inhibitor equihighly potent as SN38. TP3011 is against cancer cell lines growth with IC50s at the range sub-nanomolar in vitro. References: [1]. Anthoney DA, et al. Phase I study of TP300 in patients with advanced solid tumors with pharmacokinetic, pharmacogenetic and pharmacodynamic analyses.BMC Cancer. 2012 Nov 21;12:536. [2]. Niizuma S, et al. Synthesis of new camptothecin analogs with improved antitumor activities.Bioorg Med Chem Lett. 2009 Apr 1;19(7):2018-21.

纯度:≥98%

CAS:534605-74-8