Cefoselis sulfate (FK-037,硫酸头孢噻利) 是的第四代头孢菌素，是一种 β-内酰胺抗生素。Cefoselis sulfate 对多种革兰氏阳性和革兰氏阴性生物均表现出良好的活性。Cefoselis sulfate 可以透过血脑屏障。
| 中文别名 | 硫酸头孢噻利(cas:122841-12-7),Cefoselis sulfate |
| 英文别名 | Cefoselis sulfate;122841-12-7;5-Amino-2-{[(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}-1-(2-hydroxyethyl)-1H-pyrazol-2-ium hydrogen sulfate |
| CAS号 | 122841-12-7 |
| SMILES | O=C(C(N12)=C(CN3N(CCO)C(C=C3)=N)CS[C@]2([H])[C@H](NC(/C(C4=CSC(N)=N4)=N\OC)=O)C1=O)O.O=S(O)(O)=O |
| Inchi | InChI=1S/C19H22N8O6S2.H2O4S/c1-33-24-12(10-8-35-19(21)22-10)15(29)23-13-16(30)27-14(18(31)32)9(7-34-17(13)27)6-25-3-2-11(20)26(25)4-5-28;1-5(2,3)4/h2-3,8,13,17,20,28H,4-7H2,1H3,(H4,21,22,23,29,31,32);(H2,1,2,3,4)/b24-12-;/t13-,17-;/m1./s1 |
| InchiKey | PFMOESPYOJZCSI-GRHXURATSA-N |
| 分子式 Formula | C19H24N8O10S3 |
| 分子量 Molecular Weight | 620.64 |
| 溶解度Solubility | 生物体外In Vitro:DMSO溶解度≥ 6.4 mg/mL(10.31 mM)*"≥" means soluble可溶, but saturation unknown溶解度未知. |
| 性状 | Solid |
| 储藏条件 Storage conditions | 4℃, protect from light, stored under nitrogen * In solvent : -80℃, 6 months月; -20℃, 1 month月 (protect from light, stored under nitrogen) |
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