CD80-IN-3, a highly potent CD80 inhibitor, inhibits CD80/CD28 interaction with an EC50 of 630 nM and a Kd of 125 nM. References: [1]. Huxley P, et al. High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy. Chem Biol. 2004 Dec;11(12):1651-8.
纯度:≥98%
CAS:486449-65-4