Tos-PEG2-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

192132-77-7

C16H25NO6S

359.44

Tos-PEG2-NH-Boc

DMSO:250 mg/mL (695.53 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years