Highly potent and selective NOP receptor agonist (EC50 = 1 nM). Displays >875-fold selectivity over opioid receptors (IC50 values are 0.32, 280, >10000 and 1500 for NOP, μ, δ and κ receptors respectively). Longer lasting and 30-fold more potent than nociceptin in vivo; pronociceptive and inhibits locomotor activity.

236098-40-1

C82H137N31O22

1909.18

[Arg14,Lys15]Nociceptin

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years