Potent and selective corticotrophin releasing factor receptor 1 (CRF1) agonist (EC50 = 0.18 nM for rat CRF1). Displays anxiolytic and antidepressant activity in vivo. Microinfusion into mouse prefrontal cortex reduces defensive behavior in vivo.

TP2067

C192H323N55O63S

4442.06

Cortagine

0.01M PBS:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years