CAS NO: | 2245697-86-1 |
包装: | 50mg, 100mg, 250mg |
规格: | ≥98% |
Thalidomide-O-amido-C4-NH2 HCl, a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker, can be used in the synthesis of PROTACs. References: [1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins withPicomolar Cellular Potencies and Capable of Achieving Tumor Regression.J Med Chem. 2018 Jan 25;61(2):462-481.
[2]. James Bradner, et al. Methods to induce targeted protein degradation through bifunctional molecules. WO 2017024317 A2.
纯度:≥98%
CAS:2245697-86-1