α-Vitamin E 是一种天然存在的维生素 E，也是抗氧化剂。

(+)-α-Tocopherol is a naturally-occurring form of vitamin E, a fat-soluble vitamin with potent antioxidant properties.

vitamin E is capable of inducing necrosis in TC-1 cells and has antioxidant effects against nitric oxide[1].

Vitamin E induces TC-1 cell necrosis in vivo and reduces tumor volume in TC-1 tumor-bearing mice. Vitamin E reduces myeloid derived suppressor cells(MDSCs) in tumors of TC-1 tumor-bearing mice and enhances T cell accumulation[1].

For in vitro cytotoxicity experiments, 1×105 TC-1 cells per well are added to 24-well plates. Eighteen hours later, tumor cells are treated with Vitamin E (0, 25, 50 μM). After 18 hours, apoptotic (Annexin V+ and 7AAD−) and necrotic (Annexin V+ and 7AAD+) cells are measured using PE Annexin V Apoptosis Detection Kit I. (Only for Reference)

59-02-9

C29H50O2

430.717

5,7,8-Trimethyltocol;D-α-生育酚;Alpha-Tocopherol;Dexrabeprazole Sodium;天然维生素E;(+)-alpha-Tocopherol;D-α-Tocopherol;Vitamin E;α-Vitamin E

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years