Bis-NH2-PEG2 (PROTAC Linker 19) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

929-59-9

C6H16N2O2

148.2

PROTAC Linker 19;Bis-NH2-PEG2

DMSO:250 mg/mL (1686.91 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years