TL02-59 diHCl is an orally bioavailable, specific Src-family kinase Fgr inhibitor with an IC50 of 0.03 nM. TL02-59 diHCl inhibits Lyn and Hck with IC50s of 0.1 nM and 160 nM, respectively. TL02-59 diHCl highly potently suppresses acute myelogenous leukemia (AML) cell growth. References: [1]. Weir MC, et al. Selective Inhibition of the Myeloid Src-Family Kinase Fgr Potently Suppresses AML Cell Growth in Vitro and in Vivo. ACS Chem Biol. 2018 Jun 15;13(6):1551-1559.

纯度：≥98%

CAS：2415263-06-6