m-PEG8-O-ALKyne 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
m-PEG8-O-alkyne is a PEG-based PROTAC linker. m-PEG8-O-alkyne can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
880081-81-2
分子式
C20H38O9
分子量
422.51
别名
丙炔八甘醇单甲醚;m-PEG8-O-alkyne
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years