NH2-PEG6-C1-Boc 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
NH2-PEG6-C1-Boc is a PEG-based PROTAC linker. NH2-PEG6-C1-Boc can be used in the synthesis of PROTACs.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
297162-50-6
分子式
C18H37NO8
分子量
395.49
别名
氨基-六聚乙二醇-乙酸叔丁酯;H2N-PEG6-CH2COOtBu;NH2-PEG6-C1-Boc
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years