Potent agonist of the nociceptin (ORL1) receptor, demonstrated both in vitro and in vivo. Selective, competitive antagonism at the nociceptin receptor has also been reported (pA2 = 7.02 and 6.75 in the guinea pig ileum and mouse vas deferens respectively).

213130-17-7

C61H102N22O14

1367.6

[Phe1Ψ(CH2-NH)Gly2]Nociceptin(1-13)NH2

H2O:0.70 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years