CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor (IC50s: 0.45 and 6 nM for monkey and human CCR6), much more selective at CCR6 over human CCR1 (IC50, >30000 nM), and CCR7 (IC50, 9400 nM).

CCR6 inhibitor 1 (Compound 35) inhibits the human B cell migration L20-induced.

2437547-04-9

C24H23F3N4O3S

504.52

CCR6 inhibitor 1

DMSO:125 mg/mL (247.76 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years