APE-IN-1 是APE的有效抑制剂,IC50为 89 nM。APE-IN-1 可用于 AD 早期诊断和治疗研究。
产品描述
APE-IN-1 is a potent inhibitor of APE with IC 50 value of 89 nM. APE-IN-1 can be used for early diagnosis and drug research of AD [1].
体外活性
APE-IN-1 (5-500 nM; 24 hours) does not change cell viability in L929 normal fibroblasts at different concentrations [1]. Cell Viability Assay Cell Line: L929 cells Concentration: 5, 10, 50, 100 and 500 mM Incubation Time: 24 hours Result: Does not affected L929 cell viability, even at the higher doses.
分子式
C18H27N3O3
分子量
333.43
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years