BH3I-2' is a cell-permeable BH3 mimetic. BH3I-2' induces apoptosis by specifically preventing BH3 domain-mediated interactions between pro-apoptotic and anti-apoptotic members of the Bcl-2 family, thereby blocking the interaction between Bcl-x and Bak BH3 by targeting the Bcl-x binding pocket.

315195-18-7

C19H11Cl3INO4S

582.62

BH3I2';BH3I 2';BH3I-2'

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years