Artelinic acid, a derivative of Artemisinin, is an antimalarial drug for the treatment of multidrug-resistant strains of Plasmodium falciparum.

Artelinic acid (10 mg/kg; i.v.) has an elimination time t1/2 of 0.37 hours, a CL of 14.99 mL/min/kg, a Vss of 9.52 L, and an AUC0-12h of 11219 ng h/mL for dogs. Artelinic acid (10 mg/kg; intramuscular) has an elimination time t1/2 of 6.14 hours, a CL of 14.58 mL/min/kg, a Vss of 36.1 L and an AUC0-12h of 96372 ng h/mL for dogs. Artelinic acid (10 mg/kg; oral) has an elimination time t1/2 of 2.21 hours, a CL of 14.6 mL/min/kg, a Vss of 16.2 L and a AUC0-12h of 8839 ng h/mL for dogs [1].

120020-26-0

C23H30O7

418.48

Artelinic acid

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years