Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.

210345-02-1

C31H38F3N5O12

729.663

Ac-LETD-AFC

DMSO:10 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years