2-hydroxy Myristic acid is a hydroxy fatty acid that has been found in bovine, human, and horse milk, cow and buffalo cheeses, sea bass filet, seal oil, human vernix caseosa, and wool wax. It inhibits cleavage between the enterovirus capsid proteins VP4 and VP2, a process required for enterovirus infectivity, as well as Junin and Tacaribe viral replication (IC50s = 20.1 and 14.2 μM, respectively). 2-hydroxy Myristic acid was previously characterized as a weak inhibitor of peptide myristoylation (Ki = 200 μM) but has been shown to be inactive in ARL1 cells when used at 100 μM.

2507-55-3

C14H28O3

244.37

2-hydroxy Myristic Acid

DMF:30 mg/mL
Ethanol:PBS (1:2):0.35 mg/mL
Ethanol:37 mg/mL
DMSO:27 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years