产品描述
possesses anticancer, anti-invasive, anti-metastasis, anti-angiogenic and pro-apoptosis properties with high safety.Frondoside A, a natural glycoside extracted from the sea cucumber, Cucumaria frondosa,
体外活性
Frondoside A (0-5 μM, 24 hours)causes concentration-dependent reduction in viability of lung and breast cancer cells through a caspase 3/7-dependent cell death pathway.
体内活性
Frondoside A (0.01 and 1 mg/kg/ day i.p. for 25 days) significantly decreases the growth, the lymph node metastasis?and angiogenesis of LNM35 tumor xenografts in mice, without obvious toxic side-effects.
Cas No.
127367-76-4
分子式
C60H96NaO29S
分子量
1336.44
别名
Frondoside A
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years