AChE-IN-11 (compound 5C) 是一种很好的多功能药物 (AChEIC50= 7.9 μM, MAO-BIC50= 9.9 μM，BACE1IC50= 8.3 μM)。AChE-IN-11 表现出混合型 AChE 抑制作用，可与 AChE 的 CAS 和 PAS 结合。AChE-IN-11 还表现出良好的抗氧化活性 (ORAC = 2.5 eq) 和神经保护作用。AChE-IN-11 是一种选择性金属离子螯合剂。AChE-IN-11具有研究AD的潜力。

AChE-IN-11 (compound 5C) is a good multifunctional agent (AChE IC 50 = 7.9 μM, MAO-B IC 50 = 9.9 μM, BACE1 IC 50 = 8.3 μM). AChE-IN-11 displays a mixed-type AChE inhibition, which can bind to the CAS and PAS of AChE. AChE-IN-11 also exhibits good antioxidant activity (ORAC = 2.5 eq) and neuroprotective effects. AChE-IN-11 is a selective metal ions chelator. AChE-IN-11 has the potential for the research of AD [1].

C18H28N2O4

336.43

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years