Diheptanoyl Thio-PC is a substrate for all phospholipase A2s (PLA2s) with the exception of cPLA2 and PAF-acetyl hydrolase (PAF-AH). Interaction of this compound with a PLA2 results in cleavage of the sn-2 fatty acid generating a free thiol on the lysophospholipid. This free thiol can be detected using chromogenic substrates such as DTNB (Ellman's reagent) and DTP.

89019-63-6

C22H44NO6PS2

513.69

1,2-bis(heptanoylthio) Glycerophosphocholine

DMSO:>50 mg/mL
DMF:>50 mg/mL
Ethanol:>25 mg/mL
PBS (pH 7.2):>62 μg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years