Pregnenolone monosulfate is a powerful neurosteroid, and can protect the brain from cannabis intoxication.

The administration of the main active principle of Cannabis sativa (marijuana), Δ(9)-tetrahydrocannabinol (THC), substantially increases the synthesis of pregnenolone in the brain via activation of the type-1 cannabinoid (CB1) receptor.?Pregnenolone then, acting as a signaling-specific inhibitor of the CB1 receptor, reduces several effects of THC.

1247-64-9

C21H32O5S

396.54

3β-Hydroxy-5-pregnen-20-one monosulfate;Pregnenolone monosulfate

DMSO:62.5 mg/mL (157.61 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years