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L-2-Phosphoglyceric acid disodium salt hydrate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-2-Phosphoglyceric acid disodium salt hydrate图片
包装与价格:
包装价格(元)
1 mg电议
2 mg电议
5 mg电议
10 mg电议
25 mg电议
50 mg电议

产品名称
L-2-Phosphoglyceric acid 二钠盐水合物
产品介绍
L-2-Phosphoglyceric acid disodium salt hydrate 是一种甘油酸,可作为糖酵解第九步的底物。它被烯醇化酶催化为磷酸烯醇式丙酮酸 (PEP),这是葡萄糖转化为丙酮酸的倒数第二个步骤。

产品描述

2-Phosphoglyceric acid (2PGA) is a glyceric acid which serves as the substrate in the ninth step of glycolysis. It is catalyzed by enolase into phosphoenolpyruvate (PEP), the penultimate step in the conversion of glucose to pyruvate.

体内活性

SRT1720 (10, 30, 100 mg/kg, p.o.) significantly reduces the hyperinsulinemia after 4 weeks, partially normalizing elevated insulin levels similar to rosiglitazone treatment. SRT1720 treatment significantly reduces fasting blood glucose to near normal levels in Lepob/ob mice[1]. SRT1720 has the ability to protect against the negative effects of diet-induced obesity in mice and has a connection to metabolic adaptation in fatty acid and oxidative metabolism through downstream targets of SIRT1 such as PGC1α and FOXO1[2]. SRT1720 (50-100 mg/kg, p.o.), during emphysema development, attenuates elastase-induced airspace enlargement and lung function impairment as well as reduces arterial oxygen saturation in WT mice [3].

Cas No.

T5141

分子式

C3H5Na2O7P · xH2O

分子量

230.02

别名

L-2-Phosphoglyceric acid 二钠盐水合物;L-2-Phosphoglyceric acid disodium salt hydrate

储存和溶解度

DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years