DDO-02005 (free base) 是一种有效的Kv1.5 钙离子通道抑制剂,IC50为 0.72 μM。DDO-02005 (free base) 在CaCl2-ACh 房颤大鼠模型中具有良好的抗房颤作用,并能有效抵抗乌头碱引起的心律失常。
产品描述
DDO-02005 (free base) is a potent Kv1.5 potassium channel inhibitor with an IC 50 value of 0.72 μM. DDO-02005 (free base) has good anti-atrial fibrillation (AF) effect in CaCl 2 -ACh AF rats model and effective anti-arrhythmic activity caused by aconitine [1].
Cas No.
1186134-30-4
分子式
C21H25N3O2
分子量
351.44
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years