P-gp modulator 2 (Compound 27) 是一种有效的竞争性和变构性P-glycoprotein (P-gp)调节剂。

P-gp modulator 2 (Compound 27) is a potent, competitive, allosteric P-glycoprotein (P-gp) modulator [1].

P-gp modulator 2 (Compound 27) shows cytotoxicity on L5178Y parental (L5178Y-PAR) and human ABCB1-gene transfected (L5178Y-MDR) mouse T-lymphoma cells with IC 50 values of 8.0 ± 1.1 and 10.7 ± 1.1 μM, respectively [1].

C22H20BrN3O4

470.32

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years