您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > survivin(baculoviral IAP repeat-containing protein 5)(21-28)
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
survivin(baculoviral IAP repeat-containing protein 5)(21-28)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
survivin(baculoviral IAP repeat-containing protein 5)(21-28)图片
包装与价格:
包装价格(元)
1 mg电议
5 mg电议
10 mg电议
25 mg电议

产品名称
survivin (baculoviral IAP repeat-containing protein 5) (21-28)
产品介绍

产品描述

Survivin (baculoviral inhibitor of apoptosis IAP repeat-containing protein-5) is a member of the IAP gene family, which has been implicated in both inhibitions of apoptosis and mitosis regulation1. Survivin is one of the most uniformly up-regulated genes in tumor tissues compared with healthy tissues2. High survivin expression in the primary tumor is almost invariably associated with poor patient prognosis in many cancer types.

体外活性

Survivin relates to poor disease outcome in a variety of tumors, i.e., neuroblastoma3, colorectal cancer4, non-small-cell lung cancers5, B-cell lymphoma6, T-cell leukemia7, hepatocellular carcinoma, esophageal carcinoma, rectal cancer, glioma, bladder cancer, soft tissue sarcoma, and astrocytic tumors. Survivin mRNA, as measured by quantitative RT-PCR in the primary tumor, has strong and independent prognostic value in human breast cancer. Survivin mRNA concentrations in the tumor can be used to classify breast cancer patients into different risk groups. 8 Cells that are unresponsive to apoptotic triggers will also be more resistant to cytotoxic treatments, as are cells that overexpress survivin9.

Cas No.

TP2292

分子式

C54H73N11O11

分子量

1052.22

别名

survivin (baculoviral IAP repeat-containing protein 5) (21-28)

储存和溶解度

DMSO:≥105.2mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years