AZ-4217 is a high potency BACE inhibitor. It displays acute central efficacy in different in vivo models and reduced amyloid deposition in Tg2576 mice. AZ-4217 has IC50 160 pM in human SH-SY5Y cells with an excellent in vivo efficacy.

1383846-83-0

C30H25FN4O

476.54

AZ 4217;AZ4217;AZ-4217

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years