CCR8 antagonist 2 是一种有效的CCR8拮抗剂。CCR8 (C-C Motif 趋化因子受体 8) 主要在 Treg 细胞和 Th2 细胞上表达,但不在 Th1 细胞上表达。CCR8 antagonist 2 抑制 CCR8 活性,可用于治疗由 CCR8 介导的疾病,如癌症和/或神经性疼痛 (摘自专利 WO2022000443A1,化合物 220)。
产品描述
CCR8 antagonist 2 is a potent antagonist of CCR8. CCR8 (C-C Motif Chemokine Receptor 8) is predominantly expressed on Treg cells and Th2 cells, but not on Th1 cells. CCR8 antagonist 2 inhibits CCR8 activity, which may be used in the treatment of diseases mediated by CCR8, such as cancer, and/or neuropathic pain (extracted from patent WO2022000443A1, compound 220) [1].
Cas No.
2756350-98-6
分子式
C23H30ClN3O3S
分子量
464.02
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years