Boc-NH-O-C1-NHS ester 是一种属于 ALKyl/etHER 类的 PROTAC linker,可用于 PROTAC 分子的合成。
产品描述
Boc-NH-O-C1-NHS ester is an alkyl/ether-based PROTAC linker that can be used in PROTAC synthesis.
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
80366-85-4
分子式
C11H16N2O7
分子量
288.25
别名
[(叔丁氧羰基氨基氧]乙酸N-琥珀酰亚胺酯;Boc-NH-O-C1-NHS ester
储存和溶解度
DMSO:10 mM
Powder: -20°C for 3 years
In solvent: -80°C for 2 years