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Mc-Val-Cit-PABC-PNP
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mc-Val-Cit-PABC-PNP图片
CAS NO:159857-81-5
包装与价格:
包装价格(元)
50 mg电议
100 mg电议
500 mg电议
1 g电议

产品名称
Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate
马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇 对硝基苯基碳酸脂
产品介绍
Mc-Val-Cit-PABC-PNP 是一种组织蛋白酶可裂解的 ADC 肽接头,可用于合成抗体偶联药物。

产品描述

MC-Val-Cit-PAB-PNP, also known as Mc-Val-Cit-PABC-PNP, is a cathepsin cleavable ADC peptide linker. For example, FDA approved drug, brentuximab vedotin, adopts this linker. Protein- and peptide-drug conjugates hold a promising stance in the delivery of therapeutic agents by providing distinct advantage of improving therapeutic potential of drugs. Use of specialized linkers makes them unique in their in vivo therapeutic application by providing target tissue-specific release of drug.

Cas No.

159857-81-5

分子式

C35H43N7O11

分子量

737.767

别名

Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate;马来酰亚胺基己酰-L-缬氨酸-L-瓜氨酸对氨基苄醇 对硝基苯基碳酸脂;MC-Val-Cit-PABC-PNP

储存和溶解度

DMSO:37 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years