ThalIDOmide-5-OH 是基于 ThalIDOmide 的的cereblon配体,可用于募集CRBN蛋白。它能够利用 linker 与靶蛋白配体连接,得到 PROTAC 分子。
产品描述
Thalidomide-5-OH is the Thalidomide-based cereblon ligand that used in the recruitment of CRBN protein. It can be connected to the ligand for protein by a linker to form PROTAC.
Cas No.
64567-60-8
分子式
C13H10N2O5
分子量
274.232
别名
4 - 羟基沙利度胺;2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindoline-1,3-dione;Thalidomide-5-OH
储存和溶解度
DMSO:60 mg/mL (218.80 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years