ZXH-1-161 是一种有效的cereblon (CRBN)调节剂，在野生型 MM1.S 细胞中的IC50为 39 μM。ZXH-1-161 对 GSPT1 具有选择性降解活性。ZXH-1-161 可用于多发性骨髓瘤的研究。

ZXH-1-161 is a potent cereblon (CRBN) modulator with an IC 50 value of 39 nM in MM1.S wild type cells. ZXH-1-161 has selective degradation activity towards GSPT1. ZXH-1-161 can be used for researching multiple myeloma [1].

2407654-51-5

C26H24N6O3

468.51

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years