Boc-NH-PEG3-CH2COOH 是基于 PEG 的 PROTAC linker,用于合成 PROTAC。
产品描述
Boc-NH-PEG3-CH2COOH is a PEG-based PROTAC linker can be used in PROTAC synthesis[1].
体外活性
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
Cas No.
462100-06-7
分子式
C13H25NO7
分子量
307.34
别名
5,8,11-三氧杂-2-氮杂十三烷二酸 1-叔丁酯;Boc-NH-PEG3-CH2COOH
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years