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TPCS2a
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
TPCS2a图片
CAS NO:501083-97-2
包装:5 mg
市场价:7000元

产品名称
Tetraphenyl chlorin disulfonate
Amphinex
产品介绍
TPCS2a, also know as, tetraphenyl chlorin disulfonate, is a meso-tetraphenylchlorin substituted by two adjacent sulfonated groups with potential photosensitizing activity. Upon administration, tetraphenyl chlorin disulfonate incorporates into the cell?’s endosome and lysosome membranes. Subsequently, cytotoxic agents are administered and accumulate in endosomal and lysosomal compartments; upon local activation by light, tetraphenyl chlorin disulfonate produces Reactive Oxygen Species (ROS), such as singlet oxygen, damaging endo/lysosomal membranes and accumulated cytotoxic agents are released into the tumor cell cytosol.

产品描述

TPCS2a, also know as, tetraphenyl chlorin disulfonate, is a meso-tetraphenylchlorin substituted by two adjacent sulfonated groups with potential photosensitizing activity. Upon administration, tetraphenyl chlorin disulfonate incorporates into the cellA’s endosome and lysosome membranes. Subsequently, cytotoxic agents are administered and accumulate in endosomal and lysosomal compartments; upon local activation by light, tetraphenyl chlorin disulfonate produces reactive oxygen species (ROS), such as singlet oxygen, damaging endo/lysosomal membranes and accumulated cytotoxic agents are released into the tumor cell cytosol.

Cas No.

501083-97-2

分子式

C44H32N4O6S2

分子量

776.88

别名

Tetraphenyl chlorin disulfonate;Amphinex;TPCS2a

储存和溶解度

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years