Hydroxy-PEG10-acid 是 PEG 类 PROTAC linker。可用于合成 PROTAC 分子。

Hydroxy-PEG10-acid is a PEG-based PROTAC linker that can be used to synthesize PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

2375611-66-6

C23H46O13

530.6

HO-PEG10-CH2CH2COOH;Hydroxy-PEG10-acid

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years