您好,欢迎来到试剂仪器网! [登录] [免费注册]
试剂仪器网
位置:首页 > 产品库 > Squalamine lactate
立即咨询
咨询类型:
     
*姓名:
*电话:
*单位:
Email:
*留言内容:
请详细说明您的需求。
*验证码:
 
Squalamine lactate
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Squalamine lactate图片
CAS NO:320725-47-1
包装与价格:
包装价格(元)
5 mg电议
10 mg电议

产品名称
MSI-1256F
产品介绍

产品描述

Squalamine lactate is an aminosterol compound discovered in the tissues of the dogfish shark, with antimicrobial activity.

体外活性

Squalamine lactate has a more general effect on the cell signaling cascade, which is common to VEGF and other growth factors[1]. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin[2].

体内活性

When administered intravitreally and therefore requires intravenous dosing, Squalamine is ineffective . However, systemic dosing has yielded promising results in rats as well as humans[2].

Cas No.

320725-47-1

分子式

C37H71N3O8S

分子量

718.04

别名

MSI-1256F;Squalamine lactate

储存和溶解度

DMSO:36.66 mg/mL (51.06 mM)
Powder: -20°C for 3 years
In solvent: -80°C for 2 years