20-(tert-Butoxy)-20-oxoicosanoic acid 可以作为ADC linker或PROTAC linker，用于合成抗体偶联药物或合成 PROTAC。

20-(tert-Butoxy)-20-oxoicosanoic acid is a alkyl-chain-based PROTAC linker. 20-(tert-Butoxy)-20-oxoicosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

683239-16-9

C24H46O4

398.628

20-(tert-Butoxy)-20-oxoicosanoic acid

(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years