Sporogen-AO 1 is a fungal metabolite originally isolated fromA. oryzaethat has diverse biological activities.1,2,3,4,5It inhibits HIV-1 Tat transactivation in a cell-based assay with an IC50value of 15.8 μM.4Sporogen-AO 1 is cytotoxic to HeLa, KB, and NCI H187 cancer cells (IC50s = 8.3, 9, and 5.1 μM, respectively).2,5It is active againstC. albicans(MIC = 4 mM).3

88418-12-6

C15H20O3

248.322

Sporogen-AO 1

Dichloromethane:Soluble
DMSO:Soluble
Methanol:Soluble
Ethanol:Soluble
Powder: -20°C for 3 years
In solvent: -80°C for 2 years