IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains.

Increased levels of free Ig light chains have also been detected in various inflammatory diseases. Very recent studies have shown that Ig light chains not only activate mast cells but also dorsal root ganglia (Rijnierse, 2009)) and neutrophils (Braber and Thio (2012)), expanding their possible role as mediators in inflammatory disease.

T22856

C37H59N7O13

809.9

IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]

DMSO:≥81mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years