Inhibitor peptide corresponding to last 10 amino acids of the C-terminus of the GluA2 AMPA receptor subunit. Disrupts binding of GluA2 (at the C-terminal PDZ site) with glutamate receptor interacting protein (GRIP), AMPA receptor binding protein (ABP) and protein interacting with C kinase (PICK1). Increases amplitude of AMPA receptor-mediated currents and blocks long-term depression (LTD).

328944-75-8

C60H93N13O18

1284.47

pep2-SVKI

H2O:1 mg/mL
Powder: -20°C for 3 years
In solvent: -80°C for 2 years