GRGDSPC acetate 是硫醇化细胞粘附的 7 个氨基酸肽。
产品描述
GRGDSPC is a 7-amino acid peptide of thiolated cell adhesion.
体外活性
Thiolated cell adhesion peptides (GRGDSPC) were conjugated to acrylated dextran via thiol-acrylate reaction to regulate the interactions of human mesenchymal stem cells (hMSCs) with the photocrosslinkable hydrogels. The hydrogels permitted sustained release of short interfering RNA (siRNA) over 7 weeks and were cytocompatible with hMSCs. Sustained presentation of siRNA from these photocrosslinked DEX hydrogels enhanced the osteogenic differentiation of encapsulated hMSCs. These DEX hydrogels with tunable siRNA delivery and cell adhesive properties may provide an excellent platform for bioactive molecule delivery and tissue regeneration applications.
Cas No.
TP1759L
分子式
C27H46N10O13S
分子量
750.78
别名
GRGDSPC acetate(91575-26-7 free base);GRGDSPC;GRGDSPC acetate
储存和溶解度
(< 1 mg/ml refers to the product slightly soluble or insoluble )
Powder: -20°C for 3 years
In solvent: -80°C for 2 years