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VRK-IN-1
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
VRK-IN-1图片
CAS NO:2378855-09-3
包装与价格:
包装价格(元)
25 mg电议
50 mg电议
100 mg电议

产品介绍

产品描述

VRK-IN-1 is a potent and selective inhibitor of vaccinia-related kinases 1 (VRK1), with an IC50 of 150 nM. VRK1 is human Ser/Thr protein kinases associated with increased cell division and neurological disorders[1].

体外活性

VRK-IN-1 binds to VRK1-FL by enthalpy-driven, with a Kd of 190 nM[1].VRK-IN-1 (0.4-25 μM; 24 h) slightly decreases the viability of human HeLa cells at the concentration of 3.2 μM[1].

Cas No.

2378855-09-3

分子式

C18H11F4NO2

分子量

349.285

别名

VRK-IN-1

储存和溶解度

DMSO:100 mg/mL (286.30 mM),Need ultrasonic
Powder: -20°C for 3 years
In solvent: -80°C for 2 years